Saturday, 24 December 2011

Tramadol Dosage

Doctors should considerer a wide range of factors when prescribing medicines. The second step will be to choose the correct dose (amount and frequency). What is the meaning of dose? Dose is the measure amount of medicine, the quantity that each patient needs.
But, there is a common mistake when considering schedule for patients. Many people think that the pharmacological effects can be divided into two groups: therapeutic effects and side effects and doctors want their patients experienced only the first ones. Despite that, side effects appear and a professional method of avoiding them is to prescribe the best amount of drug. For this, there must be a previous careful evaluation of patients for better results because prescribing is a very important “medical fact”.
Physicians will vary the dose based on each patient general medical condition. The information provides in the package insert is only connected with an average amount of medicine. Thus, doctors’ general recommendations and package insert information are always useful but they need to be adjusted for each personal medical history. The amount of drug, the time between doses, and the length of the treatment will de indicated only by healthcare professionals.
What happens when patients should use medications that have special precautions when being taken? Assessment should be more careful. Many people on treatment with Tramadol ask themselves some questions about their medicine dose and administration. Sometimes they have some doubt because they must change it several times, according to their doctors’ advice. Titration is part of the treatment and it can take some time to adjust the right quantity for each individual. Tramadol dose will be different depending on the type of pain, patient medical history and any other factor that can influence on the medication dosage. Considering chronic pain, its treatment is always organized in a different way, like any other long-term treatment.
What is the dose and administration information included in Tramadol package insert? It is recommended to start at 25 mg/day. After titration, 50 to 100 mg tablets can be administered as needed every 4-6 hours in divided doses. The total daily Tramadol dosage should not exceed 400 mg/day.
The main difference between 50 mg and 100 mg Tramadol is the way patients can use the tablets. It will depend on the Tramadol dosage they have been prescribed. 50 mg Tramadol tablets can be easier to use if patient need a lower amount of Tramadol.
It is not necessary to adjust Tramadol dosage in elderly patients unless they have a renal or hepatic disorder. For elderly patients over 75, the recommended Tramadol dosage should be <300mg/day, administered in divided doses. Patients with renal or hepatic impairments and dialysis patients will receive a special dose prescribed by their physicians. Concerning patients who receive other medications, they should talk to their doctors to check if Tramadol is right for them. Cautions should be taken to avoid overdose. The lowest dose reported to be linked with fatality was likely between 500 and 1000 mg in a 40 kg woman but there are not specific details available on this case. In case of overdose, severe consequences may occur such as respiratory depression and seizure. Treatment of overdose: It is necessary to provide adequate ventilation with general supportive therapy. Naloxone will reverse some symptoms caused by overdosage with Tramadol but the danger of seizures is also increased with naloxone administration. In case of overdose, patients should contact their doctors at once or call to a toxicology center immediately. Missed dose: If patients miss Tramadol dosage, they should take it as soon as possible. If it is almost time for their next dose, they should forget the missed one and go on with their regular dosage schedule. Titration Trials: Titration is the procedure or method of establishing the right dose of a medication for each subject. It is performed by adjusting the dose gradually to achieve the desire effect. Regarding Tramadol dosage, several titration trials have been performed to test and evaluate the average dose. The information collected from these trials is also used to prepare the recommendations included in the package insert. Tramadol dosage can be better documented by titration trials and overdose is less possible.

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